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Osteo Bi-Flex® is named pharmacists’ most recommended brand of joint supplements.1

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Osteo Bi-Flex One Per Day

One Per Day

Nourish and strengthen your joints* with Osteo Bi-Flex One Per Day.

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What is Joint Shield 5-Loxin Advanced?

What is Joint Shield™?

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Osteo Bi-Flex®—Voted the #1 Best Bone & Joint Supplement. ◊

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Shop Osteo Bi-Flex® supplements online or find a store near you.

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Triple Strength with Vitamin D

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* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

† Based on three human studies with 5-LOXIN ADVANCED® where subjects rated their joint health over time, subjects’ joint health improved within 7 days, and continued to improve throughout the duration of the studies. 

 ΔRefers to level of Glucosamine HCl per tablet compared to regular strength.

 ^Inflammatory response in our body can occur from a variety of everyday factors including exercise, daily activities, physical exertion and/or other lifestyle factors.  

 ‡In a select study, participants taking Joint Shield™ 5-LOXIN ADVANCED® or placebo over 90 days rated their joint comfort during daily activities.

 ±For occasional leg cramps. 

 Individual results may vary. 

5-LOXIN ADVANCED® is a registered trademark of PLT Health Solutions – Laila Nutraceuticals, LLC. U.S. Patent #8,551,496 and patents pending.

UC-II® is a Lonza Trademark, registered in the USA.

◊ US News: Based on the results of the US News & World Report survey of pharmacists who recommend a “bone/joint supplement”, 2024.

1 Based on the results of the U.S Pharmacy Times Survey of Pharmacists’ OTC Recommendations who recommend a “joint health”
dietary supplement, 2024-2025.

Unless otherwise indicated, all trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland or used with permission. © 2022 Nestlé.