Raloxifene is a type of drug called a selective estrogen receptor modulator (SERM). It is
used to prevent osteoporosis in women after menopause.
Summary of
Interactions with Vitamins, Herbs, and Foods
(for details about the summarized interactions, read the full article)
 May be Beneficial: Depletion or
interference—The medication may deplete or interfere with the absorption or
function of the nutrient. Taking these nutrients may help replenish them. |
Phytoestrogens
|
| Side effect reduction/prevention |
None known
|
| Supportive interaction |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
| Adverse interaction |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Herbs
Formononetin
Some chemicals called phytoestrogens, found naturally in plants, have estrogen-like activity;
and some people use these phytoestrogens from dietary sources or from supplements to prevent
or treat hormone-related health problems. In test tube studies, the estrogenic activity of one
phytoestrogen, formononetin, was blocked by raloxifene.1 Further research is
necessary to determine the overall effect of raloxifene on formononetin and other
phytoestrogens in humans.
References
1. Ruh MF, Taylor JA, Howlett AC, Welshons WV. Failure of cannabinoid
compounds to stimulate estrogen receptors. Biochem Pharmacol 1997;53:35–41.
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Medicines with Vitamins and Herbs
The information presented in Healthnotes is for informational
purposes only. It is based on scientific studies (human, animal, or in vitro),
clinical experience, or traditional usage as cited in each article. The results reported may
not necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over-the-counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires March 2005.